NAFC Nutrition Coach Practice Exam 2025 - Free Nutrition Coaching Practice Questions and Study Guide

Selenium is recognized for its role in combating oxidative stress through its incorporation into selenoproteins, which are critical for the function of antioxidant enzymes such as glutathione peroxidase. These enzymes help neutralize harmful reactive oxygen species that can damage cells and tissues. By activating these protective enzymes, selenium plays an important role in maintaining cellular health and preventing oxidative damage.

While manganese also contributes to antioxidant defense by being a component of the enzyme manganese superoxide dismutase, selenium’s well-documented involvement in the specific antioxidant functions makes it particularly noteworthy. Zinc, while also imperative for many enzymatic reactions and immune function, is not uniquely known for enzyme activation against oxidation in the same manner as selenium. Lithium does not have a recognized role in antioxidant defense. Therefore, selenium stands out as the mineral directly assisting enzymes in defending against oxidation.